Comparative MR study of hepatic fat quantification using single-voxel proton spectroscopy, two-point dixon and three-point IDEAL
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چکیده
منابع مشابه
Measurement sequences for single voxel proton MR spectroscopy.
Proton spectroscopy is easy to perform at clinically used whole body MR scanners, since the necessary hardware is identical to that of MR imaging. Only specific measurements sequences for the acquisition of volume selected spectral information and appropriate evaluation software have to be installed. Several techniques for a volume-selective spectroscopy have been proposed, but only two are wid...
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Hepatic steatosis, or fatty liver, is commonly observed during the animal phase of drug safety studies. A noninvasive three-dimensional (3D) three-point Dixon method was used to quantitatively evaluate the fatty livers of rats induced by an experimental microsomal transfer protein (MTP) inhibitor, in an effort to develop a safety biomarker that could be translated to human studies. The method w...
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Introduction The use of multi-dimensional spatially-selective excitation (SSE) pulses for MR-spectroscopy (MRS) offers great potential for solving several problems generally occuring in classical volume-selective MRS with single rectangular voxels. On the one hand, the possibility of exciting arbitrarily shaped voxels, adapted to anatomical structures, can help maximizing the target-volume whil...
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Figure 1 shows the MR and MRS measurement of a patient with invasive ductal carcinoma. A: On pre-contrast images one lesion showed very dark intensity signal with irregular shape in a centered sagittal slice. The spectroscopic voxel (size, 1.6 × 1.6 × 1.6 cm) is superimposed on the hypointense lesion in the pre-contrast sagittal image. B: The MR spectrum was measured from the selected lesion. T...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2008
ISSN: 0740-3194,1522-2594
DOI: 10.1002/mrm.21561